Recombinant Human Fibronectin Protein
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产品编号
KRP700
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别名
重组人Fibronectin蛋白,FN, FN1, Fibronectin, Cold-insoluble globulin, CIG
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人Fibronectin蛋白,FN, FN1, Fibronectin, Cold-insoluble globulin, CIG |
| Catalog Number | KRP700 |
| Molecular Name | FN1 |
| Species | Human |
| Host | Sf9 Cells |
| Size | 100ug,500ug,1mg |
| Purity | >95%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.1 EU/μg, determined by LAL method. |
| Background | 一种高分子量的细胞外基质糖蛋白，通过其整合素结合域（如RGD序列）介导细胞粘附、迁移、生长和分化，在胚胎发育、伤口愈合、血栓形成及肿瘤转移中起核心作用。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 207 kDa |
| Reconstitution | It is recommended that the lyophilized human Fibronectin protein be dissolved in sterile water at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 180250 kDa |
| Uniprot ID | P02751 |
| References | 1. Mao, Y. and J.E. Schwarzbauer (2005) Matrix Biol. 24:389. 2. Potts, J.R. and I.D. Campbell (1996) Matrix Biol. 15:313. 3. Bernard, M.P. et al. (1985) Biochemistry 24:2698. 4. Kornblihtt, A.R. et al. (1983) Proc. Natl. Acad. Sci. USA 80:3218. 5. Kornblihtt, A.R. et al. (1985) EMBO J. 4:1755. 6. Mould, A.P. et al. (1991) J. Biol. Chem. 266:3579. 7. Abe, Y. et al. (2005) Biochem. Biophys. Res. Commun. 338:1640. 8. Altroff, H. et al. (2004) J. Biol. Chem. 279:55995. |
| Function | 重组人纤连蛋白，是细胞粘附、迁移和组织结构支持的关键胞外基质蛋白。适用于细胞贴壁培养支持、伤口愈合研究及组织工程支架涂层。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -44℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human Fibronectin Protein |
| Target | Fibronectin |
FAQ
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纤连蛋白是什么？
一种重要的细胞外基质糖蛋白，为细胞提供粘附位点，介导细胞粘附、铺展、迁移和信号传导。
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在干细胞培养中作为什么使用？
广泛用作无饲养层培养的细胞粘附基质，用于接种多能干细胞、造血干细胞、间充质干细胞等，提供物理支撑和整合素介导的生物活性信号。
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