Recombinant Human FLT3LG Protein, His Tag
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产品编号
KRP699
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别名
重组人Flt-3 Ligand蛋白,P36888, Flt-3 Ligand, CD135, FLK-2, FLK2, STK1
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人Flt-3 Ligand蛋白,P36888, Flt-3 Ligand, CD135, FLK-2, FLK2, STK1 |
| Catalog Number | KRP699 |
| Molecular Name | FLT3LG |
| Species | Human |
| Host | Sf9 Cells |
| Size | 100ug,500ug,1mg |
| Purity | >95%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.1 EU/μg, determined by LAL method. |
| Background | Flt-3受体（CD135）的配体，是造血干细胞、树突状细胞前体等增殖和分化的重要调节因子，在免疫治疗中作为树突状细胞的动员剂被研究。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 17.5 kDa |
| Reconstitution | It is recommended that the lyophilized human Flt-3 Ligand protein be dissolved in PBS at a concentration of 100-200 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 1730 kDa, |
| Uniprot ID | P49771 |
| References | 1. WodnarFilipowicz, A. (2003) News Physiol. Sci. 18:247. 2. Dong, J. et al. (2002) Cancer Biol. Ther. 1:486. 3. Gilliland, D.G. and J.D. Griffin (2002) Blood 100:1532. 4. Hannum, C. et al. (1994) Nature 368:643. 5. Lyman, S.D. et al. (1994) Blood 83:2795. 6. Lyman, S.D. et al. (1993) Cell 75:1157. 7. Savvides, S.N. et al. (2000) Nat. Struct. Biol. 7:486. 8. McClanahan, T. et al. (1996) Blood 88:3371. 9. Diener, K.R. et al. (2008) Exp. Hematol. 36:51. 10. Farag, S.S. and M.A. Caligiuri (2006) Blood Rev. 20:123. 11. Edwan, J.H. et al. (2004) J. Immunol. 172:5016.1. WodnarFilipowicz, A. (2003) News Physiol. Sci. 18:247. 2. Dong, J. et al. (2002) Cancer Biol. Ther. 1:486. 3. Gilliland, D.G. and J.D. Griffin (2002) Blood 100:1532. 4. Hannum, C. et al. (1994) Nature 368:643. 5. Lyman, S.D. et al. (1994) Blood 83:2795. 6. Lyman, S.D. et al. (1993) Cell 75:1157. 7. Savvides, S.N. et al. (2000) Nat. Struct. Biol. 7:486. 8. McClanahan, T. et al. (1996) Blood 88:3371. 9. Diener, K.R. et al. (2008) Exp. Hematol. 36:51. 10. Farag, S.S. and M.A. Caligiuri (2006) Blood Rev. 20:123. 11. Edwan, J.H. et al. (2004) J. Immunol. 172:5016. |
| Function | 重组人Flt-3配体，是树突状细胞和造血干细胞发育的关键生长因子。主要用于树突状细胞体外生成、免疫疗法研究及造血扩增实验。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -43℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human Flt-3 Ligand Protein |
| Target | Flt-3 |
FAQ
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FLT3配体的作用靶点是什么？
作用于表达Flt3受体（CD135）的造血干/祖细胞，对其增殖和存活至关重要。
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为什么它是造血扩增方案的核心？
因为它能特异性支持最原始的造血干/祖细胞，与SCF和TPO联用是体外高效扩增造血干细胞和祖细胞的黄金组合。
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