Recombinant Human IL-11 Protein
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产品编号
KRP698
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别名
重组人IL-11蛋白,IL-11,Interleukin-11,IL11;Adipogenesis inhibitory factor
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人IL-11蛋白,IL-11,Interleukin-11,IL11;Adipogenesis inhibitory factor |
| Catalog Number | KRP698 |
| Molecular Name | IL11 |
| Species | Human |
| Host | Sf9 Cells |
| Size | 100ug,500ug,1mg |
| Purity | >95%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.1 EU/μg, determined by LAL method. |
| Background | 一种多功能细胞因子，能刺激造血（特别是巨核细胞生成）、促进急性期蛋白产生、并参与骨代谢（抑制破骨细胞生成）和胃肠道黏膜保护。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 19 kDa |
| Reconstitution | It is recommended that the lyophilized human IL-11 protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 20 kDa |
| Uniprot ID | P20809 |
| References | 1. Putoczki, T. and M. Ernst (2010) J. Leukoc. Biol. 88:1109. 2. Paul, S.R. et al. (1990) Proc. Natl. Acad. Sci. USA 87:7512. 3. Kawashima, I. et al. (1991) FEBS Lett. 283:199. 4. Barton, V.A. et al. (2000) J. Biol. Chem. 275:36197. 5. Curtis, D.J. et al. (1997) Blood 90:4403. 6. Baumann, H. et al. (1996) J. Immunol. 157:284. 7. Karow, J. et al. (1996) Biochem. J. 318:489. |
| Function | 重组人白介素-11，是促进血小板生成和黏膜保护的重要细胞因子。常用于血小板生成研究、肠道黏膜保护实验及化疗后骨髓抑制模型。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -42℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-11 Protein |
| Target | IL-11 |
FAQ
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IL-11属于哪个家族？
主要功能？属于IL-6家族细胞因子，主要功能包括促进造血（尤其巨核细胞成熟）和参与胚胎着床过程。
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在干细胞培养中有何应用？
主要用于促进巨核细胞和血小板生成；有研究显示其可促进某些类器官（如肠道）生长；在小鼠胚胎干细胞中可部分替代LIF功能。
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