Recombinant Human TGF-β1 Protein
-
产品编号
KRP696
-
别名
重组人TGF-β1蛋白,TGFB, TGFB1, Transforming growth factor beta-1 proprotein
-
规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人TGF-β1蛋白,TGFB, TGFB1, Transforming growth factor beta-1 proprotein |
| Catalog Number | KRP696 |
| Molecular Name | TGF-β1 |
| Species | Human |
| Host | Sf9 Cells |
| Size | 100ug,500ug,1mg |
| Purity | >95%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.1 EU/μg, determined by LAL method. |
| Background | 转化生长因子β家族的多功能细胞因子，在细胞增殖、分化、凋亡、免疫调节（抑制多数免疫细胞）以及细胞外基质生成中发挥核心作用，是纤维化、癌症和免疫疾病的关键调节因子。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 12.8 kDa |
| Reconstitution | It is recommended that the lyophilized human TGF-β1 protein be dissolved in 4 mM HCl at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 10-11 kDa |
| Uniprot ID | P01137 |
| References | 1. Derynck, R. and K. Miyazono (2008) Cold Spring Harbor Laboratory Press, 29. 2. Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982. 3. Wahl, S.M. (2006) Immunol. Rev. 213:213. 4. Chang, H. et al.(2002) Endocr. Rev. 23:787. 5. Lin, J.S. et al. (2006) Reproduction 132:179. 6. Hinck, A.P. et al.(1996) Biochemistry 35:8517. 7. Mittl, P.R.E. et al. (1996) Protein Sci. 5:1261. 8. Derynck, R. et al. (1985) Nature 316:701. 9. Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407. 10. Oklu, R. and R. Hesketh (2000) Biochem. J. 352:601. 11. de Caestecker, M. et al. (2004) Cytokine Growth Factor Rev. 15:1. 12. Zuniga, J.E. et al. (2005) J. Mol. Biol. 354:1052. |
| Function | 重组人转化生长因子-β1，是调控细胞生长、分化及免疫抑制的多功能细胞因子。广泛应用于纤维化研究、免疫调节实验、干细胞分化及癌症转移模型。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -40℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human TGF-β1 Protein |
| Target | TGF-β1 |
FAQ
-
TGF-β的功能特点是什么？
具有多重、环境依赖性的功能，包括抑制细胞增殖、调节免疫、以及强力诱导细胞外基质产生和间充质分化。
-
在干细胞培养中最经典的应用是什么？
低浓度的TGF-β1/β3是诱导间充质干细胞向软骨细胞分化的金标准核心因子。此外，也用于诱导多能干细胞分化为间充质干细胞或调节性T细胞。
- 联系我们
- 电话：400-621-6806
- 手机：13116038708（微信）
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清区国际企业社区A5号楼
-
销售微信
-
官方公众号
-
400-621-6806 -
3599163699 -
周一至周五 9:00-18:00 -
-
0
-
