Recombinant Human IL15 Protein, His Tag
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产品编号
KRP694
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别名
重组人IL-15蛋白,Interleukin-15, IL-15, IL15
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人IL-15蛋白,Interleukin-15, IL-15, IL15 |
| Catalog Number | KRP694 |
| Molecular Name | IL15 |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | 结构与IL-2相似，但功能不同，主要由单核/巨噬细胞和上皮细胞等产生，是自然杀伤（NK）细胞、记忆性CD8+ T细胞发育、存活和功能维持的关键因子。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 12.5 kDa |
| Reconstitution | It is recommended that the lyophilized human IL-15 protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Uniprot ID | P40933 |
| References | 1. De Sabatino, A. et al. (2011) Cytokine Growth Factor Rev. 22:19. 2. Grabstein, K. et al. (1994) Science 264:965. 3. Tagaya, Y. et al. (1997) Proc. Natl. Acad. Sci. USA 94:14444. 4. Giri, J.G. et al. (1995) EMBO J. 14:3654. 5. Giri, J. et al. (1994) EMBO J. 13:2822. 6. Dubois, S. et al. (2002) Immunity 17:537. 7. Castillo, E.F. and K.S. Schluns (2012) Cytokine 59:479. 8. Budagian, V. et al. (2004) J. Biol. Chem. 279:40368. 9. Mortier, E. et al. (2004) J. Immunol. 173:1681. 10. Bergamaschi, C. et al. (2012) Blood 120:e1. 11. Budagian, V. et al. (2004) J. Biol. Chem. 279:42192. 12. Mortier, E. et al. (2003) J. Exp. Med. 205:1213. 13. Gordy, L.E. et al. (2011) J. Immunol. 187:6335. 14. Harris, K.M. (2011) J. Leukoc. Biol. 90:727. 15. Xia, J. et al. (2010) Clin. Immunol. 134:130. 16. Schluns, K.S. et al. (2002) J. Immunol. 168:4827. 17. Davies, E. et al. (2010) J. Leukoc. Biol. 88:529. 18. Barra, N.G. et al. (2010) Obesity 18:1601. |
| Function | 重组人白介素-15，是促进NK细胞和记忆T细胞存活与功能的关键细胞因子。常用于NK细胞扩增、免疫记忆研究及癌症免疫治疗实验。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -38℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-15 Protein |
| Target | IL-15 |
FAQ
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IL-15主要支持哪类免疫细胞？
主要支持自然杀伤细胞和记忆性CD8+ T细胞的发育、增殖、活化与存活。
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在免疫细胞治疗产品生产中的作用？
是从造血干细胞或iPSC定向、高效分化NK细胞的关键诱导因子；也是体外扩增和维持NK细胞治疗产品的核心生长因子。
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