Recombinant Human GM-CSF/CSF2 Protein, No Tag
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产品编号
KRP692
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别名
重组人GM-CSF蛋白,GMCSF, CSF2, Granulocyte-macrophage colony-stimulating factor, GM-CSF
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Catalog Number | KRP692 |
| Alias | 重组人GM-CSF蛋白,GMCSF, CSF2, Granulocyte-macrophage colony-stimulating factor, GM-CSF |
| Size | 100ug,500ug,1mg |
| Product Full Name | Recombinant Human GM-CSF Protein |
| Molecular Name | CSF2 |
| Product Introduction | 重组人粒细胞-巨噬细胞集落刺激因子，是髓系细胞分化与激活的关键调节因子。主要用于粒细胞和巨噬细胞体外分化、免疫佐剂研究及肿瘤疫苗开发。 |
| Molecular Weight | 14 kDa |
| Target | GM-CSF |
| Expression System | E.coli |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >97%, determined by SDS-PAGE. |
| Purification | Affinity Purification |
| Uniprot ID | P04141 |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -36℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | 刺激粒细胞（中性、嗜酸性）和巨噬细胞生成和功能的集落刺激因子，在炎症和免疫应答中起作用，也用于化疗后加速中性粒细胞恢复。 |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Predicted Molecular Weight | 14.5 kDa |
| Application | WB, ELISA |
| Reconstitution | It is recommended that the lyophilized human GM-CSF protein be dissolved in PBS at a concentration of 100-200 μg/ml for further dilution as the working concentration. |
| Stability | Repeated freezing and thawing is not recommended. |
| References | 1. MartinezMoczygemba, M. and D.P. Huston (2003) J. Allergy Clin. Immunol. 112:653. 2. Barreda, D.R. et al. (2004) Dev. Comp. Immunol. 28:509. 3. Eksioglu, E.A. et al. (2007) Exp. Hematol. 35:1163. 4. Cao, Y. (2007) J. Clin. Invest. 117:2362. 5. Fleetwood, A.J. et al. (2005) Crit. Rev. Immunol. 25:405. 6. Heuser, M. et al. (2007) Semin. Hematol. 44:148. 7. Hege, K.M. et al. (2006) Int. Rev. Immunol. 25:321. 8. Kaushansky, K. et al. (1992) Biochemistry 31:1881. 9. Diederichs, K. et al. (1991) Science 254:1779. 10. Cantrell, M.A. et al. (1985) Proc. Natl. Acad. Sci. 82:6250. 11. Lee, F. et al. (1985) Proc. Natl. Acad. Sci. 82:4360. 12. Wong, G.G. et al. (1985) Science 228:810. 13. OnettoPothier, N. et al. (1990) Blood 75:59. 14. Hayashida, K. et al. (1990) Proc. Natl. Acad. Sci. 87:9655. 15. Pelley, J.L. et al. (2007) Exp. Hematol. 35:1483. 16. Hogge, G.S. et al. (1990) Cancer Gene Ther. 6:26. 17. Sprague, W.S. et al. (2005) J. Comp. Pathol. 133:136. 18. Shanafelt, A.B. et al. (1991) J. Biol. Chem. 266:13804. |
| Function | 重组人粒细胞-巨噬细胞集落刺激因子，是髓系细胞分化与激活的关键调节因子。主要用于粒细胞和巨噬细胞体外分化、免疫佐剂研究及肿瘤疫苗开发。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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GM-CSF的功能是什么？粒细胞-巨噬细胞集落刺激因子，刺激髓系前体细胞分化成粒细胞和巨噬细胞/树突状细胞。
在干细胞分化中的主要用途？与IL-4联用，是体外从造血祖细胞或单核细胞生成树突状细胞的标准方案；也用于调控巨噬细胞的分化和极化。
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