Recombinant Human KITLG/SCF Protein, His Tag
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产品编号
KRP690
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别名
重组人SCF蛋白,MGF, SCF, KITLG, Kit ligand
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Catalog Number | KRP690 |
| Alias | 重组人SCF蛋白,MGF, SCF, KITLG, Kit ligand |
| Size | 100ug,500ug,1mg |
| Product Full Name | Recombinant Human SCF Protein |
| Molecular Name | KITLG |
| Product Introduction | 重组人干细胞因子，是造血干细胞和肥大细胞存活与增殖的关键因子。常用于造血干细胞体外维持、肥大细胞分化研究及组织再生实验。 |
| Target | SCF |
| Expression System | E.coli |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >97%, determined by SDS-PAGE. |
| Purification | Affinity Purification |
| Uniprot ID | P21583 |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -35℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | 也称为KIT配体，是c-KIT受体的配体，对造血干细胞、生殖细胞、黑色素细胞等多种干/祖细胞的存活、增殖和迁移至关重要。 |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Predicted Molecular Weight | 19 kDa |
| Application | WB, ELISA |
| Reconstitution | It is recommended that the lyophilized human SCF protein be dissolved in PBS at a concentration of 100 μg/mL for further dilution as the working concentration. |
| Stability | Repeated freezing and thawing is not recommended. |
| References | 1. Ashman, L.K. (1999) Int. J. Biochem. Cell Biol. 31:1037. 2. Sette, C. et al. (2000) Int. J. Dev. Biol. 44:599. 3. Yoshida, H. et al. (2001) J. Invest. Dermatol. Symp. Proc. 6:1. 4. Erlandsson, A. et al. (2004) Exp. Cell Res. 301:201. 5. Kapur, R. et al. (2002) Blood 100:1287. 6. Wang, C.H. et al. (2007) Arterioscler. Thromb. Vasc. Biol. 27:540. 7. Bashamboo, A. et al. (2006) J. Cell Sci. 119:3039. 8. Reber, L. et al. (2006) Eur. J. Pharmacol. 533:327. 9. Martin, F.H. et al. (1990) Cell 63:203. 10. Arakawa, T. et al. (1991) J. Biol. Chem. 266:18942. 11. Majumdar, M.K. et al. (1994) J. Biol. Chem. 269:1237. 12. Brannan, C.I. et al. (1991) Proc. Natl. Acad. Sci. 88:4671. 13. Anderson, D.M. et al. (1991) Cell Growth Differ. 2:373. 14. Lemmon, M.A. et al. (1997) J. Biol. Chem. 272:6311. 15. Kanellakis, P. et al. (2006) Cardiovasc. Res. 70:117 |
| Function | 重组人干细胞因子，是造血干细胞和肥大细胞存活与增殖的关键因子。常用于造血干细胞体外维持、肥大细胞分化研究及组织再生实验。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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SCF是什么？它的受体是什么？干细胞因子，是c-Kit受体（CD117）的配体，对多种干/祖细胞的存活和自我更新至关重要。
为什么它在造血干细胞培养中不可或缺？它是维持和扩增造血干细胞的基石因子，几乎所有体外的HSC扩增方案都包含SCF，它与其他因子（如TPO, FLT3-L）有强协同作用。
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