Recombinant Human IL1B Protein, His Tag
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产品编号
KRP689
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别名
IL-1β蛋白,Interleukin 1β蛋白, IL-1蛋白, IL1F2蛋白, IL1-beta蛋白, Catabolin蛋白
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | IL-1β蛋白,Interleukin 1β蛋白, IL-1蛋白, IL1F2蛋白, IL1-beta蛋白, Catabolin蛋白 |
| Catalog Number | KRP689 |
| Molecular Name | IL1B |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | 一种重要的促炎细胞因子，由NLRP3炎性小体等机制激活的巨噬细胞产生，在发热、急性期反应、炎症启动及多种自身炎症性疾病中起核心作用。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 17 kDa |
| Reconstitution | It is recommended that the lyophilized human I IL-1β protein be dissolved in PBS at a concentration of 100-200 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Uniprot ID | P01584 |
| References | 1. Allan, S.M. et al. (2005) Nat. Rev. Immunol. 5:629. 2. Boraschi, D. and A. Tagliabue (2006) Vitam. Horm. 74:229. 3. Kornman, K.S. (2006) Am. J. Clin. Nutr. 83:475S. 4. Isoda, K. and F. Ohsuzu (2006) J. Atheroscler. Thromb. 13:21. 5. March, C.J. et al. (1985) Nature 315:641. 6. Auron, P.E. et al. (1984) Proc. Natl. Acad. Sci. 81:7907. 7. Martinon, F. and J. Tschopp (2007) Cell Death Differ. 14:10. |
| Function | 重组人白介素-1β，是介导急性炎症反应和发热的关键前炎性细胞因子。广泛应用于炎症通路激活研究、免疫细胞激活实验及自身免疫性疾病模型。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -34℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human IL-1β Protein |
| Target | IL-1β |
FAQ
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IL-1β的主要功能是什么？
是一种强效的促炎细胞因子，在发热、炎症启动和免疫细胞激活中起核心作用。
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如何用于干细胞研究？
主要用于模拟炎症损伤环境。例如，研究其对间充质干细胞功能（或衰老）的影响，或构建骨关节炎等疾病的体外炎症模型。
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