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Recombinant Human IL1B Protein, His Tag

Recombinant Human IL1B Protein, His Tag

产品编号

KRP689

别名

IL-1β蛋白,Interleukin 1β蛋白, IL-1蛋白, IL1F2蛋白, IL1-beta蛋白, Catabolin蛋白

规格
  • 100ug
  • 500ug
  • 1mg
产品介绍
Catalog NumberKRP689
AliasIL-1β蛋白,Interleukin 1β蛋白, IL-1蛋白, IL1F2蛋白, IL1-beta蛋白, Catabolin蛋白
Size100ug,500ug,1mg
Product Full NameRecombinant Human IL-1β Protein
Molecular NameIL1B
Product Introduction重组人白介素-1β,是介导急性炎症反应和发热的关键前炎性细胞因子。广泛应用于炎症通路激活研究、免疫细胞激活实验及自身免疫性疾病模型。
TargetIL-1β
Expression SystemE.coli
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity >97%, determined by SDS-PAGE.
PurificationAffinity Purification
Uniprot IDP01584
Storage ConditionSamples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Temperature RangeStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -34℃. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Background一种重要的促炎细胞因子,由NLRP3炎性小体等机制激活的巨噬细胞产生,在发热、急性期反应、炎症启动及多种自身炎症性疾病中起核心作用。
Endotoxin<0.01 EU/μg, determined by LAL method.
Predicted Molecular Weight17 kDa
ApplicationWB, ELISA
ReconstitutionIt is recommended that the lyophilized human I IL-1β protein be dissolved in PBS at a concentration of 100-200 μg/ml for further dilution as the working concentration.
Stability Repeated freezing and thawing is not recommended.
References1. Allan, S.M. et al. (2005) Nat. Rev. Immunol. 5:629. 2. Boraschi, D. and A. Tagliabue (2006) Vitam. Horm. 74:229. 3. Kornman, K.S. (2006) Am. J. Clin. Nutr. 83:475S. 4. Isoda, K. and F. Ohsuzu (2006) J. Atheroscler. Thromb. 13:21. 5. March, C.J. et al. (1985) Nature 315:641. 6. Auron, P.E. et al. (1984) Proc. Natl. Acad. Sci. 81:7907. 7. Martinon, F. and J. Tschopp (2007) Cell Death Differ. 14:10.
Function重组人白介素-1β,是介导急性炎症反应和发热的关键前炎性细胞因子。广泛应用于炎症通路激活研究、免疫细胞激活实验及自身免疫性疾病模型。
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
FAQ
  • IL-1β的主要功能是什么?是一种强效的促炎细胞因子,在发热、炎症启动和免疫细胞激活中起核心作用。

    如何用于干细胞研究?主要用于模拟炎症损伤环境。例如,研究其对间充质干细胞功能(或衰老)的影响,或构建骨关节炎等疾病的体外炎症模型。

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