Recombinant Human IL2 Protein, His Tag
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产品编号
KRP686
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别名
重组人IL-2蛋白，Interleukin-2, IL-2, T-cell growth factor, TCGF
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Catalog Number | KRP686 |
| Alias | 重组人IL-2蛋白，Interleukin-2, IL-2, T-cell growth factor, TCGF |
| Size | 100ug,500ug,1mg |
| Product Full Name | Recombinant Human IL-2 Protein |
| Molecular Name | IL2 |
| Product Introduction | 重组人白介素-2，是T细胞增殖与活化的关键细胞因子。主要用于T细胞体外扩增、免疫疗法研究及癌症免疫学实验。 |
| Molecular Weight | 13 kDa |
| Target | IL-2 |
| Expression System | E.coli |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >97%, determined by SDS-PAGE. |
| Purification | Affinity Purification |
| Uniprot ID | P60568 |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -30℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | 主要由激活的T细胞产生，是T细胞（尤其是效应T细胞和调节性T细胞）生长、增殖和分化的关键因子，历史上被称为“T细胞生长因子”，是癌症免疫疗法（如IL-2疗法）和免疫抑制研究的重要靶点。 |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Predicted Molecular Weight | 15.5 kDa |
| Application | WB, ELISA |
| Reconstitution | It is recommended that the lyophilized human IL-2 protein be dissolved in 100 mM acetic acid at a concentration of 100-200 μg/ml for further dilution as the working concentration. |
| Stability | Repeated freezing and thawing is not recommended. |
| References | 1. Ma, A. et al. (2006) Annu. Rev. Immunol. 24:657. 2. Gaffen, S.L. and K.D. Liu (2004) Cytokine 28:109. 3. Taniguchi, T. et al. (1983) Nature 302:305. 4. Mosmann, T.R. et al. (1987) J. Immunol. 138:1813. 5. Liparoto, S.F. et al. (2002) Biochemistry 41:2543. 6. Wang, X. et al. (2005) Science 310:1159. 7. Bodnar, A. et al. (2008) Immunol. Lett. 116:117. 8. Jaleco, S. et al. (2003) J. Immunol. 171:61. 9. Malek, T.R. (2003) J. Leukoc. Biol. 74:961. 10. Laurence, A. et al. (2007) Immunity 26:371. 11. Kryczek, I. et al. (2007) J. Immunol. 178:6730. 12. Afzali, B. et al. (2007) Clin. Exp. Immunol. 148:32. 13. Fehervari, Z. et al. (2006) Trends Immunol. 27:109 |
| Function | 重组人白介素-2，是T细胞增殖与活化的关键细胞因子。主要用于T细胞体外扩增、免疫疗法研究及癌症免疫学实验。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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IL-2为什么被称为“T细胞生长因子”？因为它能特异性促进T淋巴细胞的增殖、活化和分化，是适应性免疫应答的关键调节因子。
在现代细胞治疗中扮演什么角色？是体外大规模扩增和激活细胞毒性T细胞、CAR-T细胞及NK细胞用于过继性免疫治疗的核心培养成分。
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