Recombinant Human M-CSF Protein
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产品编号
KRP684
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别名
重组人M-CSF蛋白，Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 重组人M-CSF蛋白，Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF |
| Catalog Number | KRP684 |
| Molecular Name | CSF1 |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | 集落刺激因子的一种，是单核/巨噬细胞系发育、分化、存活和功能激活的关键调节因子，也参与破骨细胞生成和妊娠调节。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 18.5 kDa |
| Reconstitution | It is recommended that the lyophilized human M-CSF protein be dissolved in PBS at a concentration of 50-500 μg/mL for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | 37 kDa |
| Uniprot ID | P09603 |
| References | 2. Chitu, V. and E.R. Stanley (2006) Curr. Opin. Immunol. 18:39. 3. Fixe, P. and V. Praloran (1997) Eur. Cytokine Netw. 8:125. 4. Ryan, G.R. et al. (2001) Blood 98:74. 5. Makrigiannakis, A. et al. (2006) Trends Endocrinol. Metab. 17:178. 6. Nandi, S. et al. (2006) Blood 107:786. 7. Rettenmier, C.W. and M.F. Roussel (1988) Mol. Cell Biol. 8:5026. 8. Suzu, S. et al. (1992) J. Biol. Chem. 267:16812. 9. Manos, M.M. (1988) Mol. Cell. Biol. 8:5035. 10. Koths, K. (1997) Mol. Reprod. Dev. 46:31. 11. Jang, MH. et al. (2006) J. Immunol. 177:4055. 12. Kawasaki, E.S. et al. (1985) Science 230: 291. 13. Wong, G.G. et al. (1987) Science 235:1504. |
| Function | 重组人巨噬细胞集落刺激因子，是单核/巨噬细胞系发育与活化的必需因子。常用于巨噬细胞体外分化、免疫调节研究及肿瘤相关巨噬细胞模型构建。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -28℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant Human M-CSF Protein |
| Target | M-SCF |
FAQ
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M-CSF的功能是什么？
巨噬细胞集落刺激因子，专门刺激单核/巨噬细胞系的产生、分化与功能活化。
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如何用于干细胞分化？
是驱动造血干细胞或iPSC向单核/巨噬细胞谱系分化的核心因子，可与IL-4、GM-CSF等联用以获得不同功能亚型的巨噬细胞。
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