Recombinant Human IL7 Protein, His Tag
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产品编号
KRP678
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别名
白介素7,Recombinant Human Interleukin-7; IL7; IL-7
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Catalog Number | KRP678 |
| Alias | 白介素7,Recombinant Human Interleukin-7; IL7; IL-7 |
| Size | 100ug,500ug,1mg |
| Product Full Name | Recombinant Human IL-7 Protein |
| Molecular Name | IL7 |
| Product Introduction | 重组人白介素-7，是淋巴细胞发育、存活和稳态维持所必需的细胞因子。主要用于免疫学研究、T细胞和B细胞体外扩增，以及免疫缺陷相关疾病模型构建。 |
| Target | IL-7 |
| Expression System | E.coli |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | >97%, determined by SDS-PAGE. |
| Purification | Affinity Purification |
| Uniprot ID | P13232 |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -23℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | 一种对淋巴细胞的发育与稳态至关重要的细胞因子，能促进B细胞和T细胞（尤其是初始T细胞和记忆T细胞）的存活、增殖和分化。 |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Predicted Molecular Weight | 17 kDa |
| Application | WB, ELISA |
| Reconstitution | It is recommended that the lyophilized human IL-7 protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Stability | Repeated freezing and thawing is not recommended. |
| References | 1. Sasson, S.C. et al. (2006) Curr. Drug Targets 7:1571. 2. Barata, J.T. et al. (2006) Exp. Hematol. 34:1133. 3. Goodwin, R.G. et al. (1990) Proc. Natl. Acad. Sci. USA 86:302. 4. Namen, A.E. et al. (1988) Nature 333:571. 5. Shalapour, S. et al. (2012) PLoS ONE 7: e31939. 6. Saini, M. et al. (2009) Blood 113:5793. 7. Park, J.H. et al. (2004) Immunity 21:289. 8. Vranjkovic, A. et al. (2007) Int. Immunol. 19:1329. 9. Sudo, T. et al. (1993) Proc. Natl. Acad. Sci. 90:9125. 10. Seddon, B. et al. (2003) Nat. Immunol. 4:680. 11. Schluns, K.S. et al. (2000) Nat. Immunol. 5:426. 12. Peschon, J.J. et al. (1994) J. Exp. Med. 180:1955. 13. Pribyl, J.A. and T.W. LeBien (1996) Proc. Natl. Acad. Sci. 93:10348. 14. Johnson, K. et al. (2012) J. Immunol. 188:6084. 15. Nodland, S.E. et al. (2011) Blood 118:2116. |
| Function | 重组人白介素-7，是淋巴细胞发育、存活和稳态维持所必需的细胞因子。主要用于免疫学研究、T细胞和B细胞体外扩增，以及免疫缺陷相关疾病模型构建。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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IL-7的主要生物学功能是什么？它是淋巴细胞发育的关键因子，特别对T细胞和B细胞的存活、增殖与分化至关重要。
在干细胞培养或分化中如何应用？主要应用于造血干细胞向T淋巴细胞谱系的定向分化，也是体外扩增CAR-T等免疫治疗用T细胞的关键培养因子之一。
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