Recombinant Human IGF1 Protein, No Tag
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产品编号
KRP676
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别名
胰岛素样生长因子-I ,IBP1; IGF 1; IGF I; IGF-1
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规格
- 100ug
- 500ug
- 1mg
产品介绍
| Alias | 胰岛素样生长因子-I ,IBP1; IGF 1; IGF I; IGF-1 |
| Catalog Number | KRP676 |
| Molecular Name | IGF1 |
| Species | Human |
| Host | E.coli |
| Size | 100ug,500ug,1mg |
| Purity | >97%, determined by SDS-PAGE. |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | <0.01 EU/μg, determined by LAL method. |
| Background | 一种结构与胰岛素相似的多肽激素，主要介导生长激素的作用，在细胞生长、增殖、分化和代谢（尤其合成代谢）中起关键作用，并与衰老、癌症和代谢疾病相关。 |
| Application | WB, ELISA |
| Predicted Molecular Weight | 7.6 kDa |
| Reconstitution | It is recommended that the lyophilized human IGF-I protein be dissolved in PBS at a concentration of 100 μg/ml for further dilution as the working concentration. |
| Storage Condition | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Repeated freezing and thawing is not recommended. |
| Molecular Weight | |
| Uniprot ID | P05019 |
| References | 1. Philippou, A. et al. (2007) In Vivo 21:45. 2. Sandberg-Nordqvist, A.C. et al. (1992) Brain Res. Mol. Brain Res. 12:275. 3. Guvakova, M.A. (2007) Int. J. Biochem. Cell Biol. 39:890. 4. Clemmons, D.R. (2006) Curr. Opin. Pharmacol. 6:620. 5. Bluher, S. et al. (2005) Best Pract. Res. Clin. Endocrinol. Metab. 19:577. 6. Garcia-Segura, L.M. et al. (2006) Neuroendocrinology 84:275. 7. Malemud, C.J. (2007) Clin. Chim. Acta 375:10. 8. Samani, A.A. et al. (2007) Endocrine Rev. 28:20. 9. LeRoith, D. and S. Yakar (2007) Nat. Clin. Pract. Endocrinol. Metab. 3:302. 10. Denley, A. et al. (2005) Cytokine Growth Factor Rev. 16:421. |
| Function | 带Tx标签和His标签的重组人胰岛素样生长因子-1，是一种促进细胞生长与分化的关键蛋白。常用于细胞增殖研究、代谢调控实验及组织工程中的细胞培养支持。 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -22℃. Avoid repeated freeze-thaw cycles. |
| Product Full Name | Recombinant human IGF-1 protein, Trx tag& His tag |
| Target | IGF-I |
FAQ
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什么是IGF-1，它的核心功能是什么？
胰岛素样生长因子-1，核心功能是促进细胞生长、增殖与存活，抑制细胞凋亡，并参与代谢调节。
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在干细胞培养中它主要起什么作用？
主要用于促进间充质干细胞的增殖和迁移；在神经干细胞培养中支持其存活与增殖；并参与多能干细胞向中胚层（如心肌）和内胚层（如肝细胞）的分化过程。
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