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Recombinant Mouse Noggin Protein, C-10*His tag

Recombinant Mouse Noggin Protein, C-10*His tag

产品编号

KRP364

别名

Noggin, Noggin, Noggin

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKRP364
AliasNoggin, Noggin, Noggin
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionMouse Nog(20-232 aa)
Molecular NameNog
Product IntroductionNoggin在神经发育和修复过程中发挥重要作用。。
Molecular Weight30-35 kDa
Expression SystemHEK293F Cells
SpeciesMouse
Concentration联系销售经理获得最新批次的浓度
Purity≥90%
PurificationAffinity Purification
Uniprot IDP97466
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationSupplied in PBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundEssential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:Q13253, ECO:0000269|PubMed:9585504, ECO:0000269|PubMed:9603738}.
Endotoxin< 0.1 EU per ug
Biological ActivityMeasured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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