Recombinant Mouse Noggin Protein, C-10*His tag
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产品编号
KRP364
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别名
Noggin, Noggin, Noggin
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Alias | Noggin, Noggin, Noggin |
| Catalog Number | KRP364 |
| Molecular Name | Nog |
| Molecular Weight | 30-35 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Product Description | Mouse Nog(20-232 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:Q13253, ECO:0000269|PubMed:9585504, ECO:0000269|PubMed:9603738}. |
| Species | Mouse |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4. |
| Uniprot ID | P97466 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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