Recombinant Mouse Noggin Protein, C-10*His tag
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产品编号
KRP364
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别名
Noggin, Noggin, Noggin
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规格
- 20ug
 - 50ug
 - 100ug
 - 200ug
 - 1mg
 
 
| Catalog Number | KRP364 | 
| Alias | Noggin, Noggin, Noggin | 
| Size | 20ug, 50ug, 100ug, 200ug, 1mg | 
| Product Description | Mouse Nog(20-232 aa) | 
| Molecular Name | Nog | 
| Product Introduction | Noggin在神经发育和修复过程中发挥重要作用。。 | 
| Molecular Weight | 30-35 kDa | 
| Expression System | HEK293F Cells | 
| Species | Mouse | 
| Concentration | 联系销售经理获得最新批次的浓度 | 
| Purity | ≥90% | 
| Purification | Affinity Purification | 
| Uniprot ID | P97466 | 
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. | 
| Formulation | Supplied in PBS | 
| Shipping Condition | This product is shipped on ice packs or dry ice. | 
| Background | Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:Q13253, ECO:0000269|PubMed:9585504, ECO:0000269|PubMed:9603738}. | 
| Endotoxin | < 0.1 EU per ug | 
| Biological Activity | Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 0.06-0.3 µg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4. | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
							
							
							
							
						
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