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Rhesus AGRP Protein, mFc Tag

Rhesus AGRP Protein, mFc Tag

产品编号

KMP4312

别名

重组人刺鼠相关蛋白, AGRP Protein, Rhesus AGRP Protein, mFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias重组人刺鼠相关蛋白, AGRP Protein, Rhesus AGRP Protein, mFc Tag
Catalog NumberKMP4312
Product DescriptionThe Rhesus AGRP Protein(KMP4312) is produced in HEK293 Cells. A DNA sequence encoding the Rhesus AGRP (XP_001091740.1) (Ser83-Thr132) is expressed with the Fc region of Mouse IgG1 at the N-terminus.
Molecular NameAGRP
SpeciesRhesus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundAgouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight32.3 kDa

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