Rat FSTL1 Protein, His Tag_天津卡梅德科技发展有限公司

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Rat FSTL1 Protein, His Tag

Rat FSTL1 Protein, His Tag

产品编号

KMP4257

别名

纤维蛋白相关蛋白质1, FSTL1 Protein, Rat FSTL1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	纤维蛋白相关蛋白质1, FSTL1 Protein, Rat FSTL1 Protein, His Tag
Catalog Number	KMP4257
Product Description	The Rat FSTL1 Protein(KMP4257) is produced in HEK293 Cells. A DNA sequence encoding the rat Fstl1 (NP_077345.1) (Met1-Ile306) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	FSTL1
Species	Rat
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34 kDa

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