Rat ECM1 Protein, His Tag
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产品编号
KMP4244
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别名
细胞外基质蛋白1, ECM1 Protein, Rat ECM1 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 细胞外基质蛋白1, ECM1 Protein, Rat ECM1 Protein, His Tag |
Catalog Number | KMP4244 |
Product Description | The Rat ECM1 Protein(KMP4244) is produced in HEK293 Cells. A DNA sequence encoding the rat Ecm1 (NP_446334.1) (Met1-Glu562) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | ECM1 |
Species | Rat |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 62.9 kDa |