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Rat ECM1 Protein, His Tag

Rat ECM1 Protein, His Tag

产品编号

KMP4244

别名

细胞外基质蛋白1, ECM1 Protein, Rat ECM1 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias细胞外基质蛋白1, ECM1 Protein, Rat ECM1 Protein, His Tag
Catalog NumberKMP4244
Product DescriptionThe Rat ECM1 Protein(KMP4244) is produced in HEK293 Cells. A DNA sequence encoding the rat Ecm1 (NP_446334.1) (Met1-Glu562) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameECM1
SpeciesRat
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundExtracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight62.9 kDa

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