Mouse LOXL2 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse LOXL2 Protein, His Tag

Mouse LOXL2 Protein, His Tag

产品编号

KMP4080

别名

赖氨酸-类氧化酶2, LOXL2 Protein, Mouse LOXL2 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	赖氨酸-类氧化酶2, LOXL2 Protein, Mouse LOXL2 Protein, His Tag
Catalog Number	KMP4080
Product Description	The Mouse LOXL2 Protein(KMP4080) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Loxl2 (NP_201582.2) (Met1-Gln776) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	LOXL2
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>80% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM MES, 150mM NaCl, pH6.5
Background	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme activity; and more divergent propeptide regions. LOX family enzyme activities catalyze the final enzymatic conversion required for the formation of normal biosynthetic collagen and elastin cross-links. LOXL2 is expressed by pre-hypertrophic and hypertrophic chondrocytes in vivo, and that LOXL2 expression is regulated in vitro as a function of chondrocyte differentiation. LOXL2 promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation. LOXL2 expression could also be explored as a molecular target in the prevention of breast cancer progression.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	85.9 kDa

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