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Cynomolgus CD47 Protein, His Tag

Cynomolgus CD47 Protein, His Tag

产品编号

KMP3771

别名

整合素相关蛋白, CD47 Protein, Cynomolgus CD47 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias整合素相关蛋白, CD47 Protein, Cynomolgus CD47 Protein, His Tag
Catalog NumberKMP3771
Product DescriptionThe Cynomolgus CD47 Protein(KMP3771) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus/Rhesus CD47 (XP_005548291.1/NP_001253446.1) (Met1-Asn142) is expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus CD47 sequences are identical.
Molecular NameCD47
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight15.5 kDa

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