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Cynomolgus Mesothelin Protein, His Tag

Cynomolgus Mesothelin Protein, His Tag

产品编号

KMP3747

别名

间皮素, Mesothelin Protein, Cynomolgus Mesothelin Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias间皮素, Mesothelin Protein, Cynomolgus Mesothelin Protein, His Tag
Catalog NumberKMP3747
Product DescriptionThe Cynomolgus Mesothelin Protein(KMP3747) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus MSLN (XM_005590816.3) (Asp296-Gly580) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameMesothelin
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight33.31 kDa

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