Cynomolgus IL-33 Protein
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产品编号
KMP3715
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别名
白细胞介素-33, IL-33 Protein, Cynomolgus IL-33 Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞介素-33, IL-33 Protein, Cynomolgus IL-33 Protein |
Catalog Number | KMP3715 |
Product Description | The Cynomolgus IL-33 Protein(KMP3715) is produced in E. coli. A DNA sequence encoding the Cynomolgus IL33 (XP_005581824.1) (Ser112-Ile270) is expressed with an initial Met. |
Molecular Name | IL-33 |
Species | Cynomolgus |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 18.1 kDa |