Human FGF10 Protein
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产品编号
KMP3576
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别名
成纤维细胞生长因子 10, Human FGF10 Protein, FGF10
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规格
- 50ug
- 100ug
- 200ug
Alias | 成纤维细胞生长因子 10, Human FGF10 Protein, FGF10 |
Catalog Number | KMP3576 |
Product Description | The Human FGF10 Protein(KMP3576) is produced in E. coli. The target gene encoding the mature form of human FGF10 (NP_004456.1) (Gln38-Ser208) is expressed. |
Molecular Name | FGF10 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <5.0 EU/mg determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF10 is required for normal branching morphogenesis. It may play a role in wound healing. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 19.46 kDa |