Human TGF Beta 1 & GARP Heterotrimer Protein, His Tag_天津卡梅德科技发展有限公司

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Human TGF Beta 1 & GARP Heterotrimer Protein, His Tag

Human TGF Beta 1 & GARP Heterotrimer Protein, His Tag

产品编号

KMP3566

别名

TGF Beta 1和GARP的异二聚体蛋白, Human TGF Beta 1 & GARP Heterotrimer Protein, His Tag, TGF Beta 1 & GARP Heterotrimer

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	TGF Beta 1和GARP的异二聚体蛋白, Human TGF Beta 1 & GARP Heterotrimer Protein, His Tag, TGF Beta 1 & GARP Heterotrimer
Catalog Number	KMP3566
Product Description	The Human TGF Beta 1 & GARP Heterotrimer Protein(KMP3566) is produced in HEK293 Cells. The target gene encoding the human TGFB1 (P01137)(Met1-Ser390) is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 1; The target gene encoding the human GARP (Q14392) (Met1-Asn627) is expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the TGF Beta 1 & GARP Heterotrimer is purified.
Molecular Name	TGF Beta 1 & GARP Heterotrimer
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	TGFB1 (Transforming Growth Factor Beta 1) is a Protein Coding gene. Diseases associated with TGFB1 include Camurati-Engelmann Disease and Inflammatory Bowel Disease, Immunodeficiency, And Encephalopathy. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding. An important paralog of this gene is TGFB3. GARP (LRRC32) is a type I transmembrane protein in which the extracellular region has two sets of 10 LRRs (leucine-rich repeats) regions connected by proline-rich structural domains (proline domains). In the inactive state (Latent) TGF-β forms a disulfide bond with GARP via a cysteine on its LAP.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	108.72 kDa

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