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Human LILRA2 Protein, hFc Tag

Human LILRA2 Protein, hFc Tag

产品编号

KMP3500

别名

白细胞免疫球蛋白样受体 A2, Human LILRA2 Protein, hFc Tag, LILRA2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞免疫球蛋白样受体 A2, Human LILRA2 Protein, hFc Tag, LILRA2
Catalog NumberKMP3500
Product DescriptionThe Human LILRA2 Protein(KMP3500) is produced in HEK293 Cells. The target gene encoding the human LILRA2 (NP_001124389.2) (Met1-Asn449) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameLILRA2
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundLILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils, and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. Diseases associated with LILRA2 include Tuberculoid Leprosy and Leprosy 3.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight73.7 kDa

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