Human TACI Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human TACI Protein, hFc Tag

Human TACI Protein, hFc Tag

产品编号

KMP3497

别名

亲环蛋白配体相互作用物, Human TACI Protein, hFc Tag, TACI

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	亲环蛋白配体相互作用物, Human TACI Protein, hFc Tag, TACI
Catalog Number	KMP3497
Product Description	The Human TACI Protein(KMP3497) is produced in HEK293 Cells. The target gene encoding the human TNFRSF13B (NP_036584.1) (Ser2-Thr166) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	TACI
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF13B is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. TACI/TNFRSF13B/CD267 induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	45.22 kDa

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