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Human RNF43 Protein, hFc Tag

Human RNF43 Protein, hFc Tag

产品编号

KMP3351

别名

环指蛋白 43, Human RNF43 Protein, hFc Tag, RNF43

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias环指蛋白 43, Human RNF43 Protein, hFc Tag, RNF43
Catalog NumberKMP3351
Product DescriptionThe Human RNF43 Protein(KMP3351) is produced in HEK293 Cells. The target gene encoding the human RNF43 (NP_060233.3) (Met1-Tyr197) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameRNF43
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundRNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight45.8 kDa

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