Human TNFRSF13C Protein, hFc Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human TNFRSF13C Protein, hFc Tag, Avi Tag

Human TNFRSF13C Protein, hFc Tag, Avi Tag

产品编号

KMP3341

别名

B-细胞激活因子受体, Human TNFRSF13C Protein, hFc Tag, Avi Tag, TNFRSF13C

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	B-细胞激活因子受体, Human TNFRSF13C Protein, hFc Tag, Avi Tag, TNFRSF13C
Catalog Number	KMP3341
Product Description	The Human TNFRSF13C Protein(KMP3341) is produced in HEK293 Cells. The target gene encoding the human TNFRSF13C (NP_443177.1)(Arg2-Ala71) is expressed with a c-terminal Avi tagged Fc region of human IgG1 at the C-terminus (Fc-Avi). The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	TNFRSF13C
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	35.79 kDa

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