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Human Endothelin B Receptor Protein, His Tag

Human Endothelin B Receptor Protein, His Tag

产品编号

KMP3235

别名

B 型内皮素受体, Human Endothelin B Receptor Protein, His Tag, Endothelin B Receptor

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasB 型内皮素受体, Human Endothelin B Receptor Protein, His Tag, Endothelin B Receptor
Catalog NumberKMP3235
Product DescriptionThe Human Endothelin B Receptor Protein(KMP3235) is produced in HEK293 Cells. The target gene encoding the human EDNRB (NP_000106.1) (Met1-Lys101) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameEndothelin B Receptor
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight9.5 kDa

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