Human FNDC4 Protein, mFc Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Human FNDC4 Protein, mFc Tag

Human FNDC4 Protein, mFc Tag

产品编号

KMP3233

别名

含纤连蛋白 III 型域 4, Human FNDC4 Protein, mFc Tag, FNDC4

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	含纤连蛋白 III 型域 4, Human FNDC4 Protein, mFc Tag, FNDC4
Catalog Number	KMP3233
Product Description	The Human FNDC4 Protein(KMP3233) is produced in HEK293 Cells. The target gene encoding the human FNDC4 (NP_073734.1) (Met1-Thr167) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular Name	FNDC4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of FNDC4 to different immune cell types reveals strong and specific binding to macrophages and monocytes. FNDC4 treatment of bone marrow-derived macrophages in vitro results in reduced phagocytosis, increased cell survival and reduced proinflammatory chemokine expression. Hence, treatment with FNDC4 results in a state of dampened macrophage activity, while enhancing their survival. That FNDC4 may be a factor with direct therapeutic potential in inflammatory bowel disease and possibly other inflammatory diseases.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	39.7 kDa

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0