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Human GALNT7 Protein, His Tag

Human GALNT7 Protein, His Tag

产品编号

KMP3197

别名

N-乙酰半乳糖氨基转移酶 7, Human GALNT7 Protein, His Tag, GALNT7

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasN-乙酰半乳糖氨基转移酶 7, Human GALNT7 Protein, His Tag, GALNT7
Catalog NumberKMP3197
Product DescriptionThe Human GALNT7 Protein(KMP3197) is produced in HEK293 Cells. The target gene encoding the human GALNT7 (NP_059119.2) (Pro30-Val657) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameGALNT7
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 150mM NaCl, pH7.4
BackgroundGalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. GALNT7 acts as a glycosyltransferase in protein O-glycosylation, involving in the occurrence and development of CRC. GALNT7 silencing significantly attenuated the proliferation, clonogenicity and migration of LSCC cells and induced their cycling arrest. miR-30e may function as tumor suppressors in cervical cancer through downregulation of GALNT7. Both miR-30e and its novel target, GALNT7, may play an important role in the process of cervical cancer.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight73.6 kDa

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