Human Alpha SNAP Protein, His Tag_天津卡梅德科技发展有限公司

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Human Alpha SNAP Protein, His Tag

Human Alpha SNAP Protein, His Tag

产品编号

KMP3167

别名

可溶性附着蛋白, Human Alpha SNAP Protein, His Tag, Alpha SNAP

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	可溶性附着蛋白, Human Alpha SNAP Protein, His Tag, Alpha SNAP
Catalog Number	KMP3167
Product Description	The Human Alpha SNAP Protein(KMP3167) is produced in E. coli. The target gene encoding the human NAPA (NP_003818.2) (Met1-Arg295) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	Alpha SNAP
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM Tris, 10% Glycerol, pH8.0
Background	NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of synoviolin and reduced p53 protein level. The combination of cisplatin and knockdown of NAPA represents a novel and attractive strategy to eradicate p53-sensitive cancer cells. NAPA-73 as one of the earliest neuronal markers may reflect a difference between the central and peripheral nervous systems.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	35 kDa

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