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Human TMIGD1 Protein, mFc Tag

Human TMIGD1 Protein, mFc Tag

产品编号

KMP3150

别名

含跨膜和免疫球蛋白结构域 1, Human TMIGD1 Protein, mFc Tag, TMIGD1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias含跨膜和免疫球蛋白结构域 1, Human TMIGD1 Protein, mFc Tag, TMIGD1
Catalog NumberKMP3150
Product DescriptionThe Human TMIGD1 Protein(KMP3150) is produced in HEK293 Cells. The target gene encoding the human TMIGD1 (NP_996663.1) (Met1-Pro220) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular NameTMIGD1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight47.5 kDa

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