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Human ILT4 Protein, His Tag

Human ILT4 Protein, His Tag

产品编号

KMP3135

别名

白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, ILT4

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, ILT4
Catalog NumberKMP3135
Product DescriptionThe Human ILT4 Protein(KMP3135) is produced in HEK293 Cells. The target gene encoding the human LILRB2 (AAH36827.1) (Met1-Val461) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular NameILT4
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight49.2 kDa

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