Human AGR3 Protein, mFc Tag
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产品编号
KMP3107
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别名
前梯度 3,蛋白质二硫化物异构酶家族成员, Human AGR3 Protein, mFc Tag, AGR3
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规格
- 50ug
- 100ug
- 200ug
Alias | 前梯度 3,蛋白质二硫化物异构酶家族成员, Human AGR3 Protein, mFc Tag, AGR3 |
Catalog Number | KMP3107 |
Product Description | The Human AGR3 Protein(KMP3107) is produced in HEK293 Cells. The target gene encoding the human AGR3 (NP_789783.1) (Met1-Leu166) is expressed with the Fc region of mouse IgG1 at the C-terminus. |
Molecular Name | AGR3 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been characterised as a novel potential biomarker both for breast cancer prognosis and early breast cancer detection from blood. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 43.4 kDa |