Human MMP26 Protein
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产品编号
KMP3060
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别名
基质金属肽酶 26, Human MMP26 Protein, MMP26
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规格
- 50ug
- 100ug
- 200ug
Alias | 基质金属肽酶 26, Human MMP26 Protein, MMP26 |
Catalog Number | KMP3060 |
Product Description | The Human MMP26 Protein(KMP3060) is produced in E. coli. The target gene encoding the human MMP26 (NP_068573.2) (Thr90-Pro261) is expressed and purified with an initial Met. |
Molecular Name | MMP26 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 50mM Tris, 2mM CaCl2, pH7.8 |
Background | MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. It may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin, and alpha-1 proteinase inhibitor, and is also able to activate progelatinase B. MMP26 is a target gene of miR-125b, and the expression profile of MMP26 showed an inverse relationship with miR-125b in vivo and in vitro. The overexpression of MMP26 in SW1353 cells increased cell invasiveness, while inhibition of MMP26 decreased cell invasiveness. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 19.6 kDa |