Human IL23A Protein, mFc Tag_天津卡梅德科技发展有限公司

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Human IL23A Protein, mFc Tag

Human IL23A Protein, mFc Tag

产品编号

KMP3028

别名

白细胞介素23α, Human IL23A Protein, mFc Tag, IL23A

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素23α, Human IL23A Protein, mFc Tag, IL23A
Catalog Number	KMP3028
Product Description	The Human IL23A Protein(KMP3028) is produced in HEK293 Cells. The target gene encoding the human IL23A (NP_057668.1) (Met1-Pro189) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular Name	IL23A
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised of a unique p19 subunit and p4 subunit, the latter of which is shared with IL-12. The receptor for IL-23 consists of IL-23R and IL-12Rβ1, the latter of which is also characteristic of IL-12. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling pathway. Many studies revealed that the IL-23/Th17 pathway is implicated in the pathophysiology of various autoimmune diseases, such as autoimmune arthritis, primary biliary cirrhosis, and inflammatory bowel disease.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	45 kDa

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