Human Betacellulin Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human Betacellulin Protein, hFc Tag

Human Betacellulin Protein, hFc Tag

产品编号

KMP2986

别名

Β 细胞素, Human Betacellulin Protein, hFc Tag, Betacellulin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	Β 细胞素, Human Betacellulin Protein, hFc Tag, Betacellulin
Catalog Number	KMP2986
Product Description	The Human Betacellulin Protein(KMP2986) is produced in HEK293 Cells. The target gene encoding the human BTC (P35070) (Met1-Tyr111) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	Betacellulin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of about 62-111 amino acid residues. Secondary Structure: 6% helical (1 helices; 3 residues)36% beta sheet (5 strands; 18 residues). BTC was originally identified as a growth-promoting factor in mouse pancreatic β-cell carcinoma cell line and has since been identified in humans. It plays a role in the growth and development of the neonate and/or mammary gland function. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	36 kDa

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