Human LILRB3 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human LILRB3 Protein, hFc Tag

Human LILRB3 Protein, hFc Tag

产品编号

KMP2962

别名

白细胞免疫球蛋白样受体 B3, Human LILRB3 Protein, hFc Tag, LILRB3

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞免疫球蛋白样受体 B3, Human LILRB3 Protein, hFc Tag, LILRB3
Catalog Number	KMP2962
Product Description	The Human LILRB3 Protein(KMP2962) is produced in HEK293 Cells. The target gene encoding the human LILRB3 (AAI04994.1) (Met1-Glu443) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	LILRB3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein that belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in the modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	72.9 kDa

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