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Human LRP6 Protein, hFc Tag

Human LRP6 Protein, hFc Tag

产品编号

KMP2961

别名

低密度脂蛋白受体相关蛋白6, Human LRP6 Protein, hFc Tag, LRP6

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias低密度脂蛋白受体相关蛋白6, Human LRP6 Protein, hFc Tag, LRP6
Catalog NumberKMP2961
Product DescriptionThe Human LRP6 Protein(KMP2961) is produced in HEK293 Cells. The target gene encoding the Human LRP6 (O75581) (Met1-Pro630) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameLRP6
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundLipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipoprotein (LDL) receptor-related protein-6 (LRP6) is an important co-receptor of Wnt pathway, which plays a predominant role in the development and progression of colorectal cancer. This gene, termed LDL receptor-related protein 6 (LRP6), encodes a transmembrane protein that has 71% identity and is structurally similar to the protein encoded by LRP5, a proposed candidate gene for type 1 diabetes located on human chromosome 11q13. LRP6 maps to human chromosome 12p11-p13.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight95.69 kDa

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