首页
>>
产品中心
>>
蛋白产品
>>
重组蛋白
>
Human CNTF Protein, His Tag

Human CNTF Protein, His Tag

产品编号

KMP2934

别名

绒毛神经营养因子, Human CNTF Protein, His Tag, CNTF

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias绒毛神经营养因子, Human CNTF Protein, His Tag, CNTF
Catalog NumberKMP2934
Product DescriptionThe Human CNTF Protein(KMP2934) is produced in E. coli. The target gene encoding the human CNTF (NP_000605.1) (Ala 2-Met 200) is expressed, with a polyHistide tag at the N-terminus.
Molecular NameCNTF
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCiliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. Ciliary neurotrophic factor (CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit (CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocyteands may be relevant in reducing tissue destruction during inflammatory attacks. CNTF also is a survival factor for neurons of the peripheral sensory sympathetic and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight24.5 kDa

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价