Human SCARB1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human SCARB1 Protein, hFc Tag

Human SCARB1 Protein, hFc Tag

产品编号

KMP2846

别名

清道夫受体B类成员-1, Human SCARB1 Protein, hFc Tag, SCARB1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	清道夫受体B类成员-1, Human SCARB1 Protein, hFc Tag, SCARB1
Catalog Number	KMP2846
Product Description	The Human SCARB1 Protein(KMP2846) is produced in HEK293 Cells. The target gene encoding the human SCARB1 ( NP_001076428.1) (Pro33-Tyr443) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	SCARB1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane. SCARB1 is proposed as a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells, and is involved in a wide variety of physilogical processes. As a key component in the reverse cholesterol transport pathway, SCARB1 binds high density lipoproteins (HDLs) and mediates selective cholesterol uptake by a mechanism distinct from the LDL pathway. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SCARB1 may thus serve as a useful marker that predicts variation in baseline lipid levels and postprandial lipid response. The mouse SCARB1 has been shown to exert actions in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	73.4 kDa

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