Human NGF Protein_天津卡梅德科技发展有限公司

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Human NGF Protein

Human NGF Protein

产品编号

KMP2842

别名

神经生长因子, Human NGF Protein, NGF

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	神经生长因子, Human NGF Protein, NGF
Catalog Number	KMP2842
Product Description	The Human NGF Protein(KMP2842) is produced in HEK293 Cells. The target gene encoding the human NGF (NP_002497.2, with mutation Arg 121 Gly) (Met1-Ala241) is expressed.
Molecular Name	NGF
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	24.8 kDa

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