Human IL-22BP Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human IL-22BP Protein, hFc Tag

Human IL-22BP Protein, hFc Tag

产品编号

KMP2737

别名

白细胞介素-22结合蛋白, Human IL-22BP Protein, hFc Tag, IL-22BP

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素-22结合蛋白, Human IL-22BP Protein, hFc Tag, IL-22BP
Catalog Number	KMP2737
Product Description	The Human IL-22BP Protein(KMP2737) is produced in HEK293 Cells. The target gene encoding the human IL22RA2 (NP_443194.1) (Met1-Pro263) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	IL-22BP
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in the placenta, spleen, breast, skin, and lung. It is also detected in the intestinal tract, testis, brain, heart, and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of the IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important role in the immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptors have been discovered, a membrane-bound receptor and a soluble receptor.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	55 kDa

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