Human EPOR Protein, His Tag
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产品编号
KMP2714
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别名
钙黏蛋白E, Human EPOR Protein, His Tag, EPOR
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规格
- 50ug
- 100ug
- 200ug
Alias | 钙黏蛋白E, Human EPOR Protein, His Tag, EPOR |
Catalog Number | KMP2714 |
Product Description | The Human EPOR Protein(KMP2714) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-Pro250) of human EPOR (NP_000112.1) is fused with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro. |
Molecular Name | EPOR |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 26.3 kDa |