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Human NCR3 Protein, hFc Tag

Human NCR3 Protein, hFc Tag

产品编号

KMP2628

别名

天然细胞毒性触发受体 3, Human NCR3 Protein, hFc Tag, NCR3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias天然细胞毒性触发受体 3, Human NCR3 Protein, hFc Tag, NCR3
Catalog NumberKMP2628
Product DescriptionThe Human NCR3 Protein(KMP2628) is produced in HEK293 Cells. The target gene encoding the human NCR3 (NP_001138938.1) (Met1-Gly135) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameNCR3
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNatural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight39.6 kDa

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