Human METAP1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human METAP1 Protein, His Tag

Human METAP1 Protein, His Tag

产品编号

KMP2533

别名

甲硫氨酰氨肽酶 1, Human METAP1 Protein, His Tag, METAP1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	甲硫氨酰氨肽酶 1, Human METAP1 Protein, His Tag, METAP1
Catalog Number	KMP2533
Product Description	The Human METAP1 Protein(KMP2533) is produced in Insect Cells. The target gene encoding the human METAP1 (NP_055958.2) (His52-Phe386) is expressed with a polyhistidine tag at the C-terminus and an initial Met at the N-terminus.
Molecular Name	METAP1
Species	Human
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 500mM NaCl, 10% Glycerol, pH8.0
Background	Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	39.3 kDa

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