Human AGRP Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human AGRP Protein, hFc Tag

Human AGRP Protein, hFc Tag

产品编号

KMP2472

别名

刺鼠关联蛋白, Human AGRP Protein, hFc Tag, AGRP

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	刺鼠关联蛋白, Human AGRP Protein, hFc Tag, AGRP
Catalog Number	KMP2472
Product Description	The Human AGRP Protein(KMP2472) is produced in HEK293 Cells. The target gene encoding the human AGRP (NP_001129.1) (Ser85-Thr132) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name	AGRP
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	34.1 kDa

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