Human I-309 Protein_天津卡梅德科技发展有限公司

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Human I-309 Protein

Human I-309 Protein

产品编号

KMP2471

别名

重组人趋化因子CCL1 , Human I-309 Protein, I-309

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组人趋化因子CCL1 , Human I-309 Protein, I-309
Catalog Number	KMP2471
Product Description	The Human I-309 Protein(KMP2471) is produced in E. coli. The target gene encoding the human CCL1 (P22362) (Lys24-Lys96) is expressed, with a N-terminal Met.
Molecular Name	I-309
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	40% Acetonitrile, 0.1% TFA, 20% H2O
Background	CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferation, apoptosis and adhesion. It has been demonstrated that I-309/CCL1/TCA-3 displays chemotactic activity for monocytes and other cell types such as NK cells and dendritic cells, but not for neutrophils. Furthermore, as the only known physiological ligand for CCR8, I-309/CCL1/TCA-3 was identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. I-309/CCL1/TCA-3 induces significant levels of LTC4 from elicited eosinophils.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	8.7 kDa

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