Human CD244 Protein, hFc Tag, Avi Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Human CD244 Protein, hFc Tag, Avi Tag

Human CD244 Protein, hFc Tag, Avi Tag

产品编号

KMP2465

别名

自然杀伤细胞受体2B4, Human CD244 Protein, hFc Tag, Avi Tag, CD244

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	自然杀伤细胞受体2B4, Human CD244 Protein, hFc Tag, Avi Tag, CD244
Catalog Number	KMP2465
Product Description	The Human CD244 Protein(KMP2465) is produced in HEK293 Cells. The target gene encoding the human CD244 (NP_057466.1) (Met1-Arg221) is expressed with a c-terminal Avi tagged Fc region of human IgG1 at the C-terminus (Fc-Avi). The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CD244
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of the signaling lymphocyte activation molecule (SLAM)-related receptor family and is important for stimulating NK cell cytotoxicity and cytokine production, which is expressed on all NK cells, a subpopulation of T cells, monocytes and basophils. The 2B4 antigen identified on NK cells and T cells is capable of transmitting stimulatory signals and non-MHC-restricted killing. Reported as an activating receptor, human 2B4 can effectively activate and enhance NK cell–mediated cytotoxicity, induce secretion of IFN-γ and matrix metalloproteinases (MMPs), as well as NK cell invasiveness. As a cell surface glycoprotein of the Ig-superfamily structurally related to CD2-like molecules such as CD2, CD48, CD58, CD84, Ly-9, and SLAM, 2B4 (CD244) is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. 2B4 activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	50.80 kDa

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0