Human CD27 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD27 Protein, His Tag

Human CD27 Protein, His Tag

产品编号

KMP2458

别名

肿瘤坏死因子受体超家族成员 7, Human CD27 Protein, His Tag, CD27

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体超家族成员 7, Human CD27 Protein, His Tag, CD27
Catalog Number	KMP2458
Product Description	The Human CD27 Protein(KMP2458) is produced in Insect Cells. The target gene encoding the human CD27(P26842) (Met1-Ile192) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular Name	CD27
Species	Human
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>80% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	20.77 kDa

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