Mouse CD150 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD150 Protein, His Tag

Mouse CD150 Protein, His Tag

产品编号

KMP2417

别名

信号淋巴细胞激活分子家族成员 1, Signaling Lymphocytic Activation Molecule, CD150

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMP2417
Alias	信号淋巴细胞激活分子家族成员 1, Signaling Lymphocytic Activation Molecule, CD150
Size	50ug, 100ug, 200ug
Product Description	The Mouse CD150 Protein(KMP2417) is produced in HEK293 Cells and the target gene encoding Thr25-Pro242 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD150
Product Introduction	CD150（SLAMF1）：免疫球蛋白超家族（IgSF）成员，在淋巴细胞活化和信号转导中起关键作用。
Molecular Weight	25.01 kDa
Expression System	HEK293 Cells
Species	Mouse
Purity	>95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q9QUM4
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	Signaling lymphocyte activation molecule(SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain(ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs(ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been shown to act as a coreceptor in TCR-dependent responses. SLAM, together with CD46, is one of the two receptors for measles virus. SLAM is a cell surface receptor that, like the B cell receptor, CD40, and CD95, can transmit positive or negative signals. SLAM can associate with the SH2-containing inositol phosphatase(SHIP), the SH2-containing protein tyrosine phosphatase(SHP-2), and the adaptor protein SH2 domain protein 1A. It’s upregulated on activated B cells and CD4+ and CD8+ T cells, but downregulated on Th2 polarized cells. Also, it can Inhibits antigen receptor-mediated production of IFN-gamma, but not IL-2, in CD4-/CD8- T-cells
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何储存293F细胞中表达的蛋白？

蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环，以保持蛋白的稳定性。
如何提高293F细胞中的蛋白表达效率？

可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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